Adherence Packaging

Improve patient outcomes with packaging that supports medication adherence. Ecobliss cold seal wallet technology turns your pack into an active compliance tool.
  • Calendar blister formats with clear dosing cues
  • Easy-open cold seal technology for all patient groups
  • Proven to improve refill rates by up to 30%
Discuss your adherence packaging needs

When packaging becomes part of the therapy

Medication non-adherence is one of the biggest challenges in healthcare. Around 50% of patients with chronic conditions do not take their medication as prescribed, costing the industry over EUR 25 billion annually in Europe alone. The consequences are severe: poor health outcomes, higher hospitalisation rates, and lost revenue for pharmaceutical companies.

Adherence packaging addresses this directly. By integrating dosing schedules, calendar layouts, and clear visual cues into the primary pack, your packaging becomes an active part of the treatment. Patients see at a glance whether they have taken today's dose. Complex multi-drug regimens become manageable. And the result is measurable: clinical studies show that calendar blister packs improve adherence rates by up to 30% compared to standard packaging.

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Cold seal technology: built for adherence

Ecobliss invented cold seal wallet technology and has refined it over nearly 30 years. This pressure-only sealing process requires no heat, making it suitable for sensitive medications while delivering significant sustainability benefits. The wallet format is a natural fit for adherence packaging: printed panels guide patients through their dosing schedule with day-by-day or time-of-day markings, safety instructions, and brand messaging, all integrated into a compact, portable pack.

The easy-open mechanism is critical for patient compliance. Unlike conventional push-through blisters, cold seal wallets open with minimal effort, making them accessible for elderly patients and those with reduced dexterity. Combined with tamper-evident design and optional child-resistant features through our Locked4Kids technology, you get a pack that is safe, accessible, and effective.

Explore cold seal technology
Ecobliss Pharmaceutical Packaging vignette
From concept through delivery, the project represented more than a year of development. With your expertise, persistence, patience and dedication, we created a final product that exceeded all expectations!
North-American healthcare customer
Ecobliss meets the high standards of quality and service that our company has been proud to bring to the North American Healthcare and Premium marketplace. Ecobliss is a valued partner and continues to support us as we navigate the complex marketplace.
North-American healthcare customer
Ecobliss proves to be The Smart Source. They deliver a steady and high level of integral performance. The expertise and know-how is of a very high standard. Ecobliss understands that nothing is static and proves every time its flexibility and willingness to find solutions for any new challenge.
European customer
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Tailored to your therapeutic area

Every adherence challenge is different. A titration regimen requires step-by-step dose escalation cues. A chronic maintenance therapy benefits from a 28-day calendar layout. A clinical trial pack needs clear period markings and blinding options. Ecobliss designs each adherence packaging solution from scratch, based on your specific product, dosage form, and patient population. Our in-house design and prototyping team delivers concepts within days, so you can evaluate formats quickly and move to market faster.

30 years of packaging innovation
90% of customers choose cold seal
Calendar packs improve adherence by up to 30%

Formats that fit your product

Ecobliss offers a range of adherence packaging formats to match your specific requirements. Calendar blisters with day-of-week or time-of-day markings provide clear dosing guidance for chronic therapies. Multi-panel wallets combine the blister with printed patient information, eliminating the need for a separate leaflet. Unit-dose formats ensure each dose is individually sealed and identifiable, supporting both compliance and traceability. All formats are compatible with serialisation requirements under the EU Falsified Medicines Directive and can be produced under full GMP conditions at our facility in the Netherlands.

Wat kun je verwachten?

1. Kennismaking
2. Koffie met Jamie
3. Koffie met Timo
4. Productie

Ready to improve patient adherence through smarter packaging?

Tell us about your product and therapeutic area. Our team will design a tailored adherence packaging concept and send you a sample within days.

FAQ

How does Ecobliss Pharma respond to unexpected changes in market demand?
Ecobliss Pharma has the capacity to manage unexpected volume growth or increased market demands that were not initially foreseeable. They do this by scaling up their packaging volumes. Similarly, they can scale down volumes when necessary, ensuring that they remain flexible and responsive to market changes.
What is "Pharmaceutical postponement packaging"?
"Pharmaceutical postponement packaging" refers to a service offered by Ecobliss Pharma known as Late Stage Customization. This process allows for changes or customizations to be made to the product packaging at a later stage in the supply chain, providing greater flexibility in responding to market demands.
How does Ecobliss Pharma manage small and high volume packaging?
Ecobliss Pharma uses a suite of machines that allows them to manage very small volumes of packaging and also scale up to manage unexpected volume growth or increased demands in markets. They can also scale down volumes when necessary, such as when volumes drop for any reason or when a product is at the end of its patent period.
How does Ecobliss Pharma handle country-specific packaging management?
Ecobliss Pharma recognizes the challenges posed by the ever-changing landscape of the pharmaceutical supply, such as uncertainties towards reimbursement, market accessibility, and national packaging demands that may change overnight. They have systems in place to manage these changing demands efficiently, ensuring that the right product is at the right place at the right time.
What does Ecobliss Pharma mean by "life cycle management"?
"Life cycle management" in the context of Ecobliss Pharma refers to managing the entire life cycle of a pharmaceutical product, from packaging to distribution, taking into account the changing needs and demands of different markets. This involves managing small and high volumes of packaging, adapting to changing market demands, and providing services like Late Stage Customization, also known as postponement processes.

Contact the team

Our team is the perfect combination of knowledge, experience and eagerness. Contact them by giving them a call or sending a message to let them know what a convenient time is for them to call you.
Gianni Linssen

Gianni Linssen

+31625517974
Timo Kubbinga

Timo Kubbinga

+31627348895
Jaime Wauben

Jaime Wauben

+31615446090

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