Adherence Packaging
- Calendar blister formats with clear dosing cues
- Easy-open cold seal technology for all patient groups
- Proven to improve refill rates by up to 30%

When packaging becomes part of the therapy
Medication non-adherence is one of the biggest challenges in healthcare. Around 50% of patients with chronic conditions do not take their medication as prescribed, costing the industry over EUR 25 billion annually in Europe alone. The consequences are severe: poor health outcomes, higher hospitalisation rates, and lost revenue for pharmaceutical companies.
Adherence packaging addresses this directly. By integrating dosing schedules, calendar layouts, and clear visual cues into the primary pack, your packaging becomes an active part of the treatment. Patients see at a glance whether they have taken today's dose. Complex multi-drug regimens become manageable. And the result is measurable: clinical studies show that calendar blister packs improve adherence rates by up to 30% compared to standard packaging.
Cold seal technology: built for adherence
Ecobliss invented cold seal wallet technology and has refined it over nearly 30 years. This pressure-only sealing process requires no heat, making it suitable for sensitive medications while delivering significant sustainability benefits. The wallet format is a natural fit for adherence packaging: printed panels guide patients through their dosing schedule with day-by-day or time-of-day markings, safety instructions, and brand messaging, all integrated into a compact, portable pack.
The easy-open mechanism is critical for patient compliance. Unlike conventional push-through blisters, cold seal wallets open with minimal effort, making them accessible for elderly patients and those with reduced dexterity. Combined with tamper-evident design and optional child-resistant features through our Locked4Kids technology, you get a pack that is safe, accessible, and effective.

Tailored to your therapeutic area
Every adherence challenge is different. A titration regimen requires step-by-step dose escalation cues. A chronic maintenance therapy benefits from a 28-day calendar layout. A clinical trial pack needs clear period markings and blinding options. Ecobliss designs each adherence packaging solution from scratch, based on your specific product, dosage form, and patient population. Our in-house design and prototyping team delivers concepts within days, so you can evaluate formats quickly and move to market faster.
Formats that fit your product
Ecobliss offers a range of adherence packaging formats to match your specific requirements. Calendar blisters with day-of-week or time-of-day markings provide clear dosing guidance for chronic therapies. Multi-panel wallets combine the blister with printed patient information, eliminating the need for a separate leaflet. Unit-dose formats ensure each dose is individually sealed and identifiable, supporting both compliance and traceability. All formats are compatible with serialisation requirements under the EU Falsified Medicines Directive and can be produced under full GMP conditions at our facility in the Netherlands.
Wat kun je verwachten?
Ready to improve patient adherence through smarter packaging?
Tell us about your product and therapeutic area. Our team will design a tailored adherence packaging concept and send you a sample within days.


